SubtiBank SubtiBank
yfhL [2018-02-11T23:26:59.000Z]
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yfhL [2018-02-11T23:26:59.000Z]

general stress protein, important for survival at low temperature (4°C) and during ethanol stress
locus
BSU08580
pI
11.02
mw
11.86 kDa
protein length
110 aa Sequence Blast
gene length
330 bp Sequence Blast
product
resistence protein (against toxic peptide SdpC)
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.13|Resistance against toxins/ antibiotics]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

    • Gene

    Coordinates
    929,406 → 929,738

    The protein

    Paralogous protein(s)

  • [protein|3FB5839A7A80CF52E627FF1744E50490F5CC390F|SdpI], [protein|2E0FBCA66FB88EDFD345FA289F776C7CA23976F5|YbgB]

    • [SW|Localization]

  • cell membrane (according to Swiss-Prot)

    • Expression and Regulation

    Operons

    genes
    [gene|893103B8E6163A4B403CA136A92BA3EA66DC3802|yfhK]-[gene|2B7F65B145005A8ADD2A278E3EA5A52DF162C837|yfhL]-[gene|ED478E2C37F2AD8BF06251B52511287EDB91C9EE|yfhM]
    description
    [Pubmed|10913081]

    sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|10913081,15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]
  • [protein|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW]: sigma factor, [Pubmed|9987136], in [regulon|3D974DD2967C7F8FD4E3C2AF42617B8AE9F0296D|SigW regulon]

    • regulation

  • induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]) [Pubmed|10913081,15805528]
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    Biological materials

    Mutant

  • MGNA-C364 (yfhL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2362 NBRP B. subtilis, Japan]
  • BKE08580 (Δ[gene|2B7F65B145005A8ADD2A278E3EA5A52DF162C837|yfhL]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE08580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCATCATCTCCTTTCT, downstream forward: _UP4_ACGCACAGTCAAGGAGGAGA
  • BKK08580 (Δ[gene|2B7F65B145005A8ADD2A278E3EA5A52DF162C837|yfhL]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK08580 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCATCATCTCCTTTCT, downstream forward: _UP4_ACGCACAGTCAAGGAGGAGA

    • References

  • 16629676,10913081,15805528,9987136